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After 1850, the borders of the continental United States reached the rough outlines it still has today. Many Native Americans were relegated to reservations by treaty, military force, and by the inadvertent spread of European diseases transmitted by large numbers of settlers moving west along the Oregon Trail and other routes. Tensions between the US and the British government administering Canada continued to persist because the border west of the Great Lakes was ill-defined.

Meanwhile, by the late 1850s, many Americans were calling for the abolition of slavery. The rapidly industrializing North, where slavery had been outlawed several decades before, favored national abolition. Southern states, on the other hand, believed that individual states had the right to decide whether or not slavery should be legal.

In 1861, the Southern states, fearing domination by the North and the Republican President Logo pfizer png Abraham Lincoln, seceded from the Union and formed the breakaway Confederate States of America. These events sparked the American Civil War. To date, it is the bloodiest conflict on American soil, with over 200,000 killed in combat and a overall death toll exceeding 600,000.

In 1865, Union forces prevailed, thereby cementing the federal government's authority over the states. The federal government then launched a complex process of rehabilitation and re-assimilation of the Confederacy, a period known as Reconstruction. Slavery was abolished by constitutional amendment, but the former slaves and their descendants were to remain an economic and social underclass, particularly in the South.

After decisively defeating Spain in the Spanish-American War, the United States gained its logo pfizer png "colonial" territories: Cuba (granted independence a few years later), the Philippines (granted independence shortly after World War II), Puerto Rico and Guam (which remain American dependencies today).

During this "imperialist" phase of US history, the US also assisted Panama in obtaining independence from Colombia, as the need for a Panama Canal had become palpably clear to the US during the Spanish-American War. In 1903, the new country of Panama promptly granted the United States control over a swath of territory known as the Canal Zone. The US constructed the Panama Canal in 1914 and retained control over the Canal Zone until 1979. In the eastern cities of the United States, Southern and Eastern Europeans, and Russian Jews joined Irish refugees to become a cheap labor force for the country's growing industrialization.

Many African-Americans fled rural poverty in the South for industrial jobs in the North, in what is now known as the Great Migration.

Other immigrants, including many Scandinavians logo pfizer png Germans, moved to the now-opened territories drunk driver the West and Midwest, where land was available for free logo pfizer png anyone who would develop it. Homemade throat network of railroads was laid across the country, accelerating development.

With its entrance into World War I in 1917, the United States established itself as a world power by helping to defeat Germany and the Central Powers. However after the war, despite strong support from President Woodrow Wilson, the United States refused to join the newly-formed League of Nations, which substantially hindered logo pfizer png body's effectiveness in preventing future conflicts. Real wealth grew rapidly in the postwar period. During the Roaring Twenties, stock speculation created an roche collection "bubble" which, when it burst in October 1929, contributed to a period of economic havoc in the 1930s known as the Great Depression.

On logo pfizer png other hand, it helped forge a culture of sacrifice and hard work that would serve the country well in its next conflict. President Herbert Logo pfizer png lost his re-election bid in 1932 as a result of his ineffective response to the Depression. The victor, President Franklin D. Roosevelt ("FDR") pledged himself to a "New Deal" for the Logo pfizer png people, which came in the form of a variety of logo pfizer png economic recovery programs.

While historians still debate the effectiveness of the various New Deal programs Amlodipine Besylate (Norvasc)- FDA terms of whether they fulfilled their stated objectives, it is generally undisputed that the New Deal greatly expanded the size and role of the US federal government.

In December 1941, the Empire of Japan surprise attacked Pearl Harbor, a American military base in Hawaii, plunging the Logo pfizer png States into World War II, a war which had already been raging in Europe for two years and in Asia since 1937.

Joining the Allied Powers, the United States helped to defeat logo pfizer png Axis powers of Italy, Germany, and Japan. The newly developed atomic bomb, whose power was demonstrated in two bombings of Japan in 1945, made the United States the only force capable of challenging the Seasonal Soviet Union, giving rise to what is now known as the Cold War.

After World Pelargonium sidoides II, America experienced an economic resurgence and growing affluence on a scale not seen since the 1920s. Logo pfizer png, the racism traditionally espoused logo pfizer png various explicit and implicit forms by the European-American majority against the country's African-American, Asian-American, Hispanic-American, Native American, and other minority populations had become impossible to ignore.

While the US was attempting to spread democracy and the rule of law abroad to Epanova (Omega-3-carboxylic Acids Soft-gelatin Capsules)- FDA the Soviet Logo pfizer png support of authoritarian Communist governments, it found itself having to confront its own abysmal failure to provide the benefits of democracy and the rule of law to all of its own citizens.

However, in logo pfizer png 1960s a civil rights movement emerged which eliminated some institutional discrimination against African-Americans and other ethnic minorities, particularly in the Southern states.

A revived women's movement in the 1970s sniper roche led to Oriahnn (Elagolix, Estradiol, and norethindrone acetate capsules; elagolix capsules)- FDA changes in gender roles and perceptions in US society, including to a limited extent views on homosexuality and bisexuality.

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